[DOWNLOAD] "Resistance to Molecular Therapies for Hepatocellular Carcinoma" by Augusto Villanueva * Book PDF Kindle ePub Free
eBook details
- Title: Resistance to Molecular Therapies for Hepatocellular Carcinoma
- Author : Augusto Villanueva
- Release Date : January 14, 2017
- Genre: Medical,Books,Professional & Technical,
- Pages : * pages
- Size : 2179 KB
Description
This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies.